Microdosing is a term that has gained popularity in recent years. From Silicon Valley entrepreneurs to therapists, from creative minds to those struggling with mental symptoms - more and more people are discovering the subtle power of low-dose psychedelics. But what exactly is microdosing? And why does it seem to work so well, especially when using psilocybin from magic truffles or magic mushrooms? This blog post will give you a clear and scientifically based answer.


What is microdosing?


Microdosing means taking a very small amount of a psychedelic substance, usually about 1/10th to 1/20th of a normal "trip dose". The aim is not to hallucinate or completely detach from reality, but rather to subtly expand your consciousness, improve your mood, or increase your concentration.

When microdosing psilocybin, people often use magic truffles (legally available in the Netherlands), which contain the active substance psilocybin. This substance is converted in the body into psilocin, which binds to serotonin receptors in the brain - in particular the 5-HT2A receptor. This leads to changes in brain activity, but at microdoses this happens at such a subtle level that you usually don't "feel" it directly, but do experience effects.


Why microdosing with psilocybin?


Psilocybin has been proven in numerous studies to be a potent substance in the treatment of depression, anxiety disorders, PTSD and addiction, among others. Most studies focus on full psychedelic sessions, but in recent years the number of studies and anecdotal reports on microdosing has been growing.

Microdosing with psilocybin works on a different level than a 'full trip'. Users often report:

  • More focus and clarity
  • Emotional stability
  • Enhanced creativity
  • Deeper connection with self and others
  • Less brooding thoughts
  • Improved sleep rhythm
  • Reduction of anxiety and gloominess


How does microdosing work on a neurological level?

The brain is not a static organ. Neuroplasticity - the brain's ability to make new connections - is essential for learning, adaptation and healing. Psilocybin stimulates this plasticity in several ways:

1. Increased BDNF production
BDNF stands for Brain-Derived Neurotrophic Factor. This protein plays an important role in the growth, survival and repair of neurons. Psilocybin increases BDNF production, leading to improved mood, learning ability and resilience.

2. Connection between brain regions
Psilocybin increases communication between normally separate brain areas. This creates new perspectives, insights and solutions to old thinking patterns. When microdosing, this happens in a mild way, allowing you to function normally in everyday life, but with more flexibility and openness.

3. Decrease in activity of the Default Mode Network (DMN)
The DMN is active when you are brooding, over-analysing yourself, or stuck in negative self-images. Psilocybin dampens this activity, giving room for calmness and a more objective view of yourself.


Why does microdosing work better for some people than others?


While many people benefit from microdosing, it does not work equally well for everyone. This is due to several factors:

  • Individual neurochemistry
  • Dosage and protocol (e.g. Fadiman: 1 day yes, 2 days no)
  • Intentionality and integration: journaling, meditation, coaching

Is microdosing legal?


In the Netherlands, fresh magic truffles are legally available. They contain the same active substance as magic mushrooms, but are not considered a banned substance. This makes the Netherlands unique within Europe. Microdosing with magic mushrooms, on the other hand, is punishable in many countries.

Finally, what can you expect?
Microdosing is not a quick fix. Don't expect euphoria or instant healing, but subtle changes that build slowly. Combined with self-reflection, healthy habits and a safe environment, microdosing can be a catalyst for a conscious, resilient and inspired life.

Want to know more about how to safely start microdosing with psilocybin truffles yourself? Then read more about the different protocols at: https://microdosingxp.com/nl/microdosing-xp/